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Invitrogen
CCR1 Polyclonal Antibody
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产品信息
PA1-21629
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues T(7) E D Y D T T T E F D Y G D A T P C(24) of human CCR1.
偶联物
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA1-21629 detects CCR1 in human and mouse samples.
PA1-21629 has been successfully used in ELISA, immunocytochemistry, immunohistochemistry (paraffin) and Western blot procedures.
PA1-21629 immunogen corresponds to Synthetic peptide: TEDYDTTTEFDYGDATPC (Human).
Note: This antibody is an F(ab')2 IgG fragment.
靶标信息
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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