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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD142 Antibodies

          Invitrogen

          CD142 Monoclonal Antibody (TF9-10H10)

          2 篇参考文献
          查看其他10个CD142抗体

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          说明书
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          Cite CD142 Monoclonal Antibody (TF9-10H10)

          CD142 Monoclonal Antibody (TF9-10H10)

          产品信息

          MA1-83495

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          Assay-dependent
          -

          免疫组化 (IHC)

          -
          查看2篇已发表文章 2篇已发表文章

          免疫组化(冰冻) (IHC (F))

          Assay-dependent
          -

          免疫细胞化学 (ICC/IF)

          Assay-dependent
          -

          流式细胞分析 (Flow)

          Assay-dependent
          -
          产品规格

          种属反应

          Human, Non-human primate

          已发表种属

          Cynomolgus monkey, Rhesus monkey

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          TF9-10H10

          抗原

          denatured tissue factor isolated from human brain by the Factor VII affinity method
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Protein G

          保存液

          PBS with 0.1M mannitol

          内含物

          <0.1% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2101347

          产品详细信息

          This antibody does not react with rabbit.

          Mouse anti Human CD142 antibody, clone TF9-10H10 recognizes human CD142, also known as Tissue Factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation.

          靶标信息

          This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          生物信息学

          蛋白别名: CD142; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); TF; Thromboplastin; Tissue factor

          查看更多 收起

          基因别名: CD142; F3; TF; TFA

          查看更多 收起

          UniProt ID: (Human) P13726

          查看更多 收起

          Entrez Gene ID: (Human) 2152

          查看更多 收起

          功能
          protease binding serine-type endopeptidase activity cytokine receptor activity protein binding phospholipid binding transmembrane signal receptor
          参与通路
          positive regulation of endothelial cell proliferation activation of plasma proteins involved in acute inflammatory response activation of blood coagulation via clotting cascade activation of cysteine-type endopeptidase activity involved in apoptotic process aging blood coagulation blood coagulation, extrinsic pathway response to temperature stimulus response to mechanical stimulus positive regulation of platelet-derived growth factor receptor signaling pathway positive regulation of smooth muscle cell migration protein processing cytokine-mediated signaling pathway positive regulation of cell migration response to estradiol response to lipopolysaccharide response to fluid shear stress positive regulation of angiogenesis positive regulation of positive chemotaxis positive regulation of protein kinase B signaling response to low-density lipoprotein particle cellular response to hydrogen peroxide
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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