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Invitrogen
CD148 Polyclonal Antibody
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产品信息
PA1-27626
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to human Receptor-type tyrosine-protein phosphatase eta.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-27626 detects PTPRJ from human samples.
PA1-27626 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The immunogen is a synthetic peptide corresponding to human Receptor-type tyrosine-protein phosphatase eta.
靶标信息
CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found broadly on fibroblasts, epithelial cells, lymphocytes (B, T and NK cells), and myeloid cells (monocytes and granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-gamma, and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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