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Proteintech
CD177 Polyclonal Antibody
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产品信息
18264-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CD177 fusion protein Ag13146
偶联物
形式
Liquid
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: TVQHVWKVSD LPRQWTPKNT SCDSGLGCQD TLMLIESGPQ VSLVLSKGCT EAKDQEPRVT EHRMGPGLSL ISYTFVCRQE DFCNNLVNSL PLWAPQPPAD PGSLRCPVCL SMEGCLEGTT EEICPKGTTH CYDGLLRLRG GGIFSNLRVQ GCMPQPGCNL LNGTQEIGPV GMTENCNRKD FLTCHRGTTI MTHGNLAQEP TDWTTSNTEM CEVGQVCQET LLLLDVGLTS TLVGTKGCST VGAQNSQKTT IHSAPPGVLV ASYTHFCSSD LCNSASSSSV LLNSLPPQAA PVPGDRQCPT CVQPLGTCSS GSPRMTCPRG TTHCYDGYIH LSGGGLSTKM SIQGCVAQPS SFLLNHTRQI GIFSAREKRD VQPPASQHEG GGAEGLESL
靶标信息
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD177; CD177 antigen; cell surface receptor; HNA-2a; Human neutrophil alloantigen 2a; NB1 glycoprotein; NB1 GP; Polycythemia rubra vera protein 1; PRV-1
基因别名: 1190003K14Rik; CD177; HNA-2a; HNA2A; NB1; NB1 GP; Pdp3; PRV-1; PRV1; UNQ595/PRO1181
UniProt ID: (Human) Q8N6Q3, (Mouse) Q8R2S8
Entrez Gene ID: (Human) 57126, (Mouse) 68891
