Exalpha

CD2/CD20 Antibody Cocktail, FITC, PE

Name: CD2\/CD20 Antibody Cocktail, FITC, PE
Brand: Exalpha
SKU: 0220S
Price: ... USD
Availability: InStock

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

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Immunogen image

Immunogen Image CD2/CD20 Antibody Cocktail, FITC, PE

产品信息

0220S

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

10 µL/1x10^6 cells in a 100 µL suspension

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, IgG2a

分类

Cocktail

类型

Antibody

抗原

CD2 was derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with t lymphocytes activated by mixed lymphocyte culture.CD20 was derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with the LB lymphoblastoid cell line.

3D表位/免疫原

偶联物

FITC , PE FITC , PE FITC , PE

形式

Liquid

纯化类型

Protein A/G

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20°C, Avoid Freeze/Thaw Cycles, store in dark

Ambient (domestic); Wet ice (international)

产品详细信息

Flow Cytometry PBMC: Add 10 µL of MAB/10^6 PBMC in 100 µL PBS. Mix gently and incubate for 15 minutes at 2 to 8C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze.

Flow Cytometry Whole Blood: Add10 µL of MAB/100 µL of whole blood. Mix gently and incubate for 15 minutes at room temperature 20C. Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturer instructions for Lysed Whole Blood and Immunofluorescence analysis with a flow cytometer or microscope.

靶标信息

CD2 is found on the majority of human T and NK cells. CD2 presents on 78+8% normal peripheral lymphocytes and 100% of thymocytes. This antibody detects CD2 antigen CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation. It is expressed in all B cell precursor leukemias.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: 2CD2 antigen; B-lymphocyte cell-surface antigen B1; CD2 antigen (p50), sheep red blood cell receptor; CD2 surface antigen; CD20 antigen; CD20 receptor; erythrocyte receptor; leukocyte surface antigen Leu-16; LFA-3 receptor; lymphocyte-function antigen-2; membrane-spanning 4-domains, subfamily A, member 1; MGC3969; rosette receptor; surface antigen CD2 precursor; T-cell surface antigen CD2 precursor; T-cell surface antigen T11/Leu-5; unnamed protein product

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基因别名: B1; Bp35; CD20; CVID5; FMC7; LEU-16; LFA-2; S7; SRBC; T11

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UniProt ID: (Human) P06729, (Human) P11836

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Entrez Gene ID: (Human) 914, (Human) 931

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功能

receptor binding protein binding protein kinase binding receptor tyrosine kinase binding signaling receptor activity identical protein binding epidermal growth factor receptor binding immunoglobulin binding MHC class II protein complex binding

参与通路