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Invitrogen
CD249 Polyclonal Antibody
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CD249 Antibody (PA5-88487) in WB
Western blot analysis of CD249 in extracts of various cell lines. Samples were incubated with CD249 Polyclonal antibody (Product # PA5-88487) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88487
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 850-950 of human ENPEP (NP_0019683)
偶联物
形式
Liquid
浓度
0.74 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VFTVIRYISY NSYGKNMAWN WIQLNWDYLV NRYTLNNRNL GRIVTIAEPF NTELQLWQME SFFAKYPQAG AGEKPREQVL ETVKNNIEWL KQHRNTIREW F; Positive Samples: 293T, LO2, HT-29, Mouse liver; Cellular Location: Membrane, Single-pass type II membrane protein
靶标信息
CD249 appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Aminopeptidase A; aminopeptidase-A; AP-A; BP-1/6C3 antigen; BP1; CD249; Differentiation antigen gp160; EAP; Glutamyl aminopeptidase; glutamyl aminopeptidase (aminopeptidase A)
基因别名: 6030431M22Rik; APA; Bp-1/6C3; CD249; ENPEP; gp160; Ly-51; Ly51
UniProt ID: (Human) Q07075, (Mouse) P16406
Entrez Gene ID: (Human) 2028, (Mouse) 13809
angiogenesis
angiotensin maturation
angiotensin catabolic process in blood
regulation of systemic arterial blood pressure by renin-angiotensin
cell-cell signaling
cell proliferation
cell migration
glomerulus development
peptide catabolic process
proteolysis
cellular aromatic compound metabolic process
