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Invitrogen
CD300a Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-139739
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: SGDHSELSQN PKQASPREEL HYASVVFDSN TNRIAAQRPR EEEPDSDYSV IRK
Highest antigen sequence indentity to the following orthologs: Rat - 41%, Mouse - 31%.
靶标信息
The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998 [PubMed 9701027]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD300 antigen-like family member A; CD300a antigen; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35HIRp60; immunoglobulin superfamily member 12; inhibitory receptor protein 60; IRC1a; IRC1b; IRC1c; leukocyte membrane antigen; Mcipr1; NK inhibitory receptor; NKRL
基因别名: CLM-8; CMRF-35-H9; CMRF-35H; CMRF35-H; CMRF35-H9; CMRF35H; CMRF35H9; IGSF12; IRC1; IRC1/IRC2; IRC2; IRp60
UniProt ID: (Human) Q9UGN4
Entrez Gene ID: (Human) 11314
signal transduction
negative regulation of B cell proliferation
negative regulation of mast cell activation involved in immune response
negative regulation of MyD88-dependent toll-like receptor signaling pathway
intracellular signal transduction
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
regulation of innate immune response
negative regulation of fibroblast proliferation
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of eosinophil migration
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
