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Invitrogen
CD45RO Monoclonal Antibody (IL-A116), PE
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CD45RO Antibody (MA5-28402) in Flow
Flow cytometry of CD45RO in red cell lysed bovine blood. Sample was incubated in the presence of 10% rat serum, CD45RO monoclonal antibody (Product # MA5-28402) and gated on lymphoid cells. Figures are arranged as follows: A) FITC conjugated Mouse anti Bovine CD4 Antibody and RPE conjugated Mouse IgG3 isotype control. B) FITC conjugated Mouse anti Bovine CD4 Antibody and RPE conjugated Mouse anti Bovine CD45RO Antibody.
产品信息
MA5-28402
产品规格
种属反应
Bovine
宿主/亚型
Mouse
/ IgG3
分类
Monoclonal
类型
Antibody
克隆号
IL-A116
抗原
Bovine peripheral blood mononuclear cells
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Lyophilized
浓度
Conc. Not Determined
纯化类型
Protein A
保存液
PBS with 5% sucrose, 1% BSA
内含物
0.09% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Mouse anti Bovine CD45RO, clone IL-A116 recognizes the bovine homologue of the human CD45RO cell surface antigen.
Reconstitute by adding 1 mL distilled water.
靶标信息
CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RO is expressed on macrophages, CD8+ T cells, activated T cells and myeloma cells. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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