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Invitrogen
CD46 Monoclonal Antibody (M177), FITC
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产品信息
MA5-49013
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
M177
抗原
Purified MCP
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
100 µg/mL
保存条件
4°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The monoclonal antibody M177 reacts with the SCR2 domain.
靶标信息
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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