NeoBiotechnologies

CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (SPV-L14)

Name: CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (SPV-L14)
Brand: NeoBiotechnologies
SKU: 923-MSM3-P0

查看其他44个CD6抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)

CD6 (Negative Marker of T-regulatory Cells) Antibody in Immunocytochemistry (ICC/IF)

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CD6 (Negative Marker of T-regulatory Cells) Antibody (923-MSM3-P0) in ICC/IF

Immunofluorescence staining of MOLT4 cells using CD6 Mouse Monoclonal Antibody (SPV-L14) followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are stained with RedDot.

CD6 (Negative Marker of T-regulatory Cells) Antibody in Flow Cytometry (Flow)

CD6 (Negative Marker of T-regulatory Cells) Antibody in SDS-PAGE (SDS-PAGE)

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产品信息

923-MSM3-P0

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

1-2 µg/mL

流式细胞分析 (Flow)

1-2 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

SPV-L14

抗原

CD8+ cytotoxic T-cell clone

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4°C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。