Leinco Technologies

CD71 Monoclonal Antibody (T56/14), Functional Grade, In Vivo GOLD™

Name: CD71 Monoclonal Antibody (T56\/14), Functional Grade, In Vivo GOLD\u2122
Brand: Leinco Technologies
SKU: C371-1MG

高级验证

查看其他131个Transferrin Receptor (CD71)抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

Additional Information:

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CD71 Antibody (C371-1MG)

Antibody clone (T56/14) specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. Loss of signal was observed for target protein in CD71 KO cells (blue histogram) compared to the control Cas9 cells (pink histogram) using CD71 antibody (T56/14). Yellow histogram represents staining with the isotype control. {KO}

Product Image Gallery

CD71 Antibody — Antibody clone (T56/14) specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. Loss of signal was observed for target protein in CD71 KO cells (blue histogram) compared to the control Cas9 cells (pink histogram) using CD71 antibody (T56/14). Yellow histogram represents staining with the isotype control. {KO}

产品信息

C371-1MG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化 (IHC)

Assay-dependent

流式细胞分析 (Flow)

Assay-dependent

免疫沉淀 (IP)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

T56/14

抗原

Proprietary immunogen

偶联物

Functional Grade Functional Grade Functional Grade

形式

Liquid

浓度

≥5.0 mg/mL

1 mg

纯化类型

Protein A/G

保存液

PBS, pH 7.2-7.4

内含物

no preservative

保存条件

4°C short term, -80°C long term

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Specificity: Clone T56/14 recognizes human CD71.

Endotoxin Level: ≤ 1.0 EU/mg as determined by the LAL method. Purity: >95% by SDS Page; ≥95% monomer by analytical SEC.

Product Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80 C. Avoid Repeated Freeze Thaw Cycles.

This antibody has been tested in the following applications: Western Blotting, Flow Cytometry.

靶标信息

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

仅用于科研。不用于诊断过程。未经明确授权不得转售。