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Proteintech
CD97 Monoclonal Antibody (3F10C2), CoraLite® Plus 488
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CD97 Antibody (CL488-66972) in Flow
1X10^6 Jurkat cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human CD97 (CL488-66972, Clone:3F10C2) (red), or 0.4 µg Mouse IgG2a Isotype Control (CL488-66360-2, Clone: K11A1B2A2) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
产品信息
CL488-66972
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
3F10C2
抗原
Recombinant protein
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: QDSRGCARWC PQNSSCVNAT ACRCNPGFSS FSEIITTPTE TCDDINECAT PSKVSCGKFS DCWNTEGSYD CVCSPGYEPV SGAKTFKNES ENTCQDVDEC SSGQHQCDSS TVCFNTVGSY SCRCRPGWKP RHGIPNNQKD TVCEDMTFST WTPPPGVHSQ TLSRFFDKVQ DLGRDSKTSS AEVTIQNVIK LVDELMEAPG DVEALAPPVR HLIATQLLSN LEDIMRILAK SLPKGPFTYI SPSNTELTLM IQERGDKNVT MGQSSARMKL NWAVAAGAED PGPAVAGILS IQNMTTLLAN ASLNLHSKKQ AELEEIYESS IRGVQLRRLS
靶标信息
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adhesion G protein-coupled receptor E5; CD97; CD97 antigen; CD97 molecule; EGF-TM7 receptor; Leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation
基因别名: AA409984; ADGRE5; CD97; TM7LN1
UniProt ID: (Human) P48960, (Mouse) Q9Z0M6
Entrez Gene ID: (Human) 976, (Mouse) 26364
