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Proteintech
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Immunogen sequence: MLILKQLVS SSVHSKRRSR ADLTAEMISA PLGDFRHTMH VGRAGDAFGD TSFLNSKAGE PDGESLDEQP SSSSSKRSLL SRKFRGSKRS QSVTRGEREQ RDMLGSLRDS ALFVKNAMSL PQLNEKEAAE KGTSKLPKSL SSSPVKKAND GEGGDEEAGT EEAVPRRNGA AGPHSPDPLL DEQAFGDLTD LPVVPKATYG LKHAESIMSF HIDLGPSMLG DVLSIMDKEE WDPEEGEGGY HGDEGAAGTI TQAPPYAVAA PPLARQEGKA GPDLPSLPSH ALEDEGWAAA APSPGSARSM GSHTTRDSSS LSSCTSGILE ERSPAFRGPD RARAAVSRQP DKEFSFMDEE EEDEIRV (1-356 aa encoded by BC010451)
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: binder of Rho GTPase 4; Binder of Rho GTPases 4; CDC42 effector protein (Rho GTPase binding) 4; Cdc42 effector protein 4; MGC17125; MGC3740
基因别名: 1500041M20Rik; BORG4; CDC42EP4; CEP4; KAIA1777
UniProt ID: (Human) Q9H3Q1, (Mouse) Q9JM96
Entrez Gene ID: (Human) 23580, (Mouse) 56699, (Rat) 303653