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Proteintech
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Immunogen sequence: MDARRVPQK DLRVKKNLKK FRYVKLISME TSSSSDDSCD SFASDNFANT RLQSVREGCR TRSQCRHSGP LRVAMKFPAR STRGATNKKA ESRQPSENSV TDSNSDSEDE SGMNFLEKRA LNIKQNKAML AKLMSELESF PGSFRGRHPL PGSDSQSRRP RRRTFPGVAS RRNPERRARP LTRSRSRILG SLDALPMEEE EEEDKYMLVR KRKTVDGYMN EDDLPRSRRS RSSVTLPHII RPVEEITEEE LENVCSNSRE KIYNRSLGST CHQCRQKTID TKTNCRNPDC WGVRGQFCGP CLRNRYGEEV RDALLDPNWH CPPCRGICNC SFCRQRDGRC ATGVLVYLAK YHGFGNVHAY LKSLKQEFEM QA (1-371 aa encoded by BC027966)
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: c-Myc target JPO1; Cell division cycle-associated protein 7; Protein JPO1
基因别名: 2310021G01Rik; AU044109; CDCA7; ICF3; JPO1
UniProt ID: (Human) Q53EW5, (Rat) Q4KM91, (Mouse) Q9D0M2
Entrez Gene ID: (Human) 83879, (Rat) 311742, (Mouse) 66953