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Leinco Technologies
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Specificity: Clone 9A2 recognizes an epitope within the extracellular domain of human/mouse CDCP1.
Endotoxin Level: <1.0 EU/mg as determined by the LAL method.
Purity: ≥95% monomer by analytical SEC and >95% by SDS Page.
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
CDCP1 is a transmembrane protein containing three extracellular CUB domains. It is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. CDCP1 is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD318; CUB domain-containing protein 1; gp140; Membrane glycoprotein gp140; SIMA135; Subtractive immunization M plus HEp3-associated 135 kDa protein; Transmembrane and associated with src kinases
基因别名: 9030022E12Rik; AA409659; CD318; CDCP1; E030027H19Rik; SIMA135; TRASK; UNQ2486/PRO5773
UniProt ID: (Human) Q9H5V8, (Mouse) Q5U462
Entrez Gene ID: (Human) 64866, (Mouse) 109332