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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cadherin; cadherin 20, type 2; cadherin 7; Cadherin-20; Cadherin-7
基因别名: Cad20; CDH20; Cdh7; CDH7L3
UniProt ID: (Human) Q9HBT6, (Rat) Q5DWV1, (Mouse) Q9Z0M3
Entrez Gene ID: (Human) 28316, (Rat) 363948, (Mouse) 23836