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Invitrogen
CDH23 Polyclonal Antibody
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产品信息
PA5-102659
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CDH23(Accession Q9H251), corresponding to amino acid residues K445-V495.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CDH23.
靶标信息
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: age related hearing loss 1; bobby; bustling; Cadherin; cadherin 23; cadherin 23 (otocadherin); cadherin related 23; Cadherin-23; cadherin-like 23; cadherin-related family member 23; DFNB12; DKFZp434P2350; FLJ00233; FLJ36499; MGC102761; modifier of deaf waddler; Otocadherin; OTTHUMP00000044780; USH1H; waltzer; Waltzing
基因别名: 4930542A03Rik; ahl; ahl1; bob; bus; CDH23; CDHR23; KIAA1774; KIAA1812; mdfw; nmf112; nmf181; nmf252; sals; UNQ1894/PRO4340; USH1D; v; W
UniProt ID: (Human) Q6UWW1, (Mouse) Q99PF4, (Rat) P58365
Entrez Gene ID: (Human) 64072, (Mouse) 22295, (Rat) 114102
calcium ion transport
homophilic cell adhesion via plasma membrane adhesion molecules
visual perception
sensory perception of sound
locomotory behavior
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
photoreceptor cell maintenance
response to stimulus
sensory perception of light stimulus
equilibrioception
regulation of cytosolic calcium ion concentration
inner ear receptor stereocilium organization
cell adhesion
adult locomotory behavior
inner ear morphogenesis
auditory receptor cell differentiation
post-embryonic organ morphogenesis
inner ear development
righting reflex
auditory receptor cell stereocilium organization
biological_process
