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Invitrogen
CDH23 Polyclonal Antibody
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CDH23 Antibody (PA5-53564) in IHC (P)
Cell reports 2023 -
Figure 5. Immature type I and type II vestibular hair cells in IEOs (A) UMAP plot of annotated human inner ear atlas highlighting hair cells (HCs). (B) UMAP plot comparing reference hair cell population (left) and mapped IEO-derived hair cell population (right) using Symphony. (C) Density plots of reference hair cell population (left) for immature, type I, and type II vestibular markers, and density plots o... View More
产品信息
PA5-53564
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human CDH23
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: YFVVDIVARD LAGHNDTAII GIYILRDDQR VKIVINEIPD RVRGFEEEFI HLLSNITGAI VNTDNVQFHV DKKGRVNFAQ TELLIHVVNR DTNRILDVDR VIQMIDENKE QLRNLFRNYN VLD
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 58%.
靶标信息
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
