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Invitrogen
CDK1 Polyclonal Antibody
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产品信息
PA5-120839
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 198-297 of human CDK1 (NP_0017771)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.24 mg/mL
规格
24 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: MCF7, Jurkat, C6, Mouse kidney. The target is usually found in the following locations: Cytoplasm, Mitochondrion, Nucleus, centrosome, cytoskeleton, microtubule organizing center, spindle.
Immunogen sequence: ATKKPLFHGD SEIDQLFRIF RALGTPNNEV WPEVESLQDY KNTFPKWKPG SLASHVKNLD ENGLDLLSKM LIYDPAKRIS GKMALNHPYF NDLDNQIKKM
靶标信息
CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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