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Invitrogen
CDSN Polyclonal Antibody
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CDSN Antibody (PA5-89932) in WB
Western blot analysis of CDSN in extracts of various cell lines. Samples were incubated with CDSN Polyclonal antibody (Product # PA5-89932) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-89932
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDSN (NP_0012553)
偶联物
形式
Liquid
浓度
1.29 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GGSAGSFKPG TGYSQVSYSS GSGSSLQGAS GSSQLGSSSS HSGSSGSHSG SSSSHSSSSS SFQFSSSSFQ VGNGSALPTN DNSYRGILNP SQPGQSSSSS Q; Positive Samples: BXPC-3, A-431, NIH/3T3, Mouse Skin, Mouse skeletal muscle, Rat skin, Rat skeletal muscle
靶标信息
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Corneodesmosin; D6S586E; differentiated keratinocyte S protein; S protein; similar to corneodesmosin
基因别名: AI747712; CDSN; HTSS; HTSS1; HYPT2; PSS; PSS1; S
UniProt ID: (Human) B0S7V2, (Mouse) Q7TPC1
Entrez Gene ID: (Human) 1041, (Mouse) 386463, (Rat) 682408
