Proteintech

CENPJ Polyclonal Antibody

Name: CENPJ Polyclonal Antibody
Brand: Proteintech
SKU: 11517-1-AP

61 篇参考文献

查看其他10个CENPJ抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (5)

CENPJ Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 5

CENPJ Antibody (11517-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using 11517-1-AP (CENPJ antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

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Immunogen image

Immunogen Image CENPJ Polyclonal Antibody

产品信息

11517-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看19篇已发表文章 19篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

1:10-1:100

查看38篇已发表文章 38篇已发表文章

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

不适用 (N/A)

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse, Rat, Zebrafish

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

CENPJ Fusion Protein Ag2078 (1033-1338 aa encoded by BC024209)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.45 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: RENTDLREE IKVMERFRLD AWKRAEAIES SLEVEKKDKL ANTSVRFQNS QISSGTQVEK YKKNYLPMQG NPPRRSKSAP PRDLGNLDKG QAASPREPLE PLNFPDPEYK EEEEDQDIQG EISHPDGKVE KVYKNGCRVI LFPNGTRKEV SADGKTITVT FFNGDVKQVM PDQRVIYYYA AAQTTHTTYP EGLEVLHFSS GQIEKHYPDG RKEITFPDQT VKNLFPDGQE ESIFPDGTIV RVQRDGNKLI EFNNGQRELH TAQFKRREYP DGTVKTVYAN GHQETKYRSG RIRVKDKEGN VLMDTEL (1033-1338 aa encoded by BC024209)

靶标信息

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: CENP-J; Centromere protein J; Centrosomal P4.1-associated protein; LAG-3-associated protein; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; microcephaly

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基因别名: 4932437H03Rik; BM032; CENP-J; CENPJ; CPAP; Gm81; LAP; LIP1; MCPH6; Sas-4; Sas4; SASS4; SCKL4

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UniProt ID: (Human) Q9HC77, (Mouse) Q569L8

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Entrez Gene ID: (Human) 55835, (Rat) 305909, (Mouse) 219103

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功能

protein binding tubulin binding protein kinase binding protein domain specific binding transcription coactivator activity gamma-tubulin binding cytoskeletal protein microtubule or microtubule-binding cytoskeletal protein

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