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Proteintech
CETP Polyclonal Antibody
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产品信息
13459-1-AP
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CETP Fusion Protein Ag3923 (144-493 aa encoded by BC025739)
偶联物
形式
Liquid
浓度
0.23 mg/mL
规格
34.5 µg
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TQLTCDSGR VRTDAPDCYL SFHKLLLHLQ GEREPGWIKQ LFTNFISFTL KLVLKGQICK EINVISNIMA DFVQTRAASI LSDGDIGVDI SLTGDPVITA SYLESHHKGH FIYKNVSEDL PLPTFSPTLL GDSRMLYFWF SERVFHSLAK VAFQDGRLML SLMGDEFKAV LETWGFNTNQ EIFQEVVGGF PSQAQVTVHC LKMPKISCQN KGVVVNSSVM VKFLFPRPDQ QHSVAYTFEE DIVTTVQASY SKKKLFLSLL DFQITPKTVS NLTESSSESI QSFLQSMITA VGIPEVMSRL EVVFTALMNS KGVSLFDIIN PEIITRDGFL LLQMDFGFPE HLLVDFLQSL S (144-493 aa encoded by BC025739)
靶标信息
It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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