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Invitrogen
CHCHD4 Polyclonal Antibody
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CHCHD4 Antibody (PA5-106395) in ICC/IF
Immunofluorescent analysis of CHCHD4 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CHCHD4 polyclonal antibody (Product # PA5-106395) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-106395
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CHCHD4(Accession Q8N4Q1), corresponding to amino acid residues S2-N52.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CHCHD4.
靶标信息
CHCHD4, a component of human mitochondria, belongs to a protein family whose members share 6 highly conserved cysteine residues constituting a -CXC-CX(9)C-CX(9)C- motif in the C terminus (Hofmann et al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Coiled-coil-helix-coiled-coil-helix domain-containing protein 4; mitochondrial intermembrane space import and assembly 40 homolog; Mitochondrial intermembrane space import and assembly protein 40; translocase of inner mitochondrial membrane 40 homolog
基因别名: 2410012P20Rik; 2810014D17Rik; AI838740; CHCHD4; MIA40; TIMM40
UniProt ID: (Human) Q8N4Q1, (Mouse) Q8VEA4, (Rat) Q5BJN5
Entrez Gene ID: (Human) 131474, (Mouse) 72170, (Rat) 312559
transport
protein transport
protein maturation by protein folding
cellular response to oxidative stress
mitochondrial DNA repair
protein import into mitochondrial intermembrane space
regulation of protein export from nucleus
'de novo' posttranslational protein folding
oxidation-reduction process
establishment of protein localization to mitochondrion
positive regulation of cellular respiration
