Invitrogen

CHD1L Polyclonal Antibody

Name: CHD1L Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-31440

高级验证

查看其他12个CHD1L抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)
高级验证 (1)

图: 1 / 3

CHD1L Antibody (PA5-31440) in WB

Western Blot using CHD1L Polyclonal Antibody (Product # PA5-31440). Sample (30 µg of whole cell lysate). Lane A: HepG2 . Lane B: HepG2 nucleus . 5% SDS PAGE. CHD1L Polyclonal Antibody (Product # PA5-31440) diluted at 1:3,000.

CHD1L Antibody in Immunoprecipitation (IP)

Product Image Gallery

CHD1L Antibody — Antibody specificity was demonstrated by shRNA mediated knockdown of target protein. 293T cells were transfected with CHD1L shRNA and decrease in signal intensity was observed in Western blotting using Anti-CHD1L Polyclonal Antibody (Product # PA5-31440). {KD}

产品信息

PA5-31440

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:10,000

免疫沉淀 (IP)

1:100-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.02 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2548914

产品详细信息

Recommended positive controls: 293T, HepG2, HepG2 nucleus.

Predicted reactivity: Mouse (92%), Bovine (93%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: amplified in liver cancer 1; Amplified in liver cancer protein 1; chromodomain helicase DNA binding protein 1-like; Chromodomain-helicase-DNA-binding protein 1-like

查看更多收起

基因别名: ALC1; CHD1L; CHDL

查看更多收起

UniProt ID: (Human) Q86WJ1

查看更多收起

Entrez Gene ID: (Human) 9557

查看更多收起

功能

nucleotide binding nucleic acid binding ATP-dependent DNA helicase activity protein binding ATP binding ATPase activity

参与通路