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Invitrogen
CHI3L1 Polyclonal Antibody
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CHI3L1 Antibody (PA5-81355) in WB
Western blot was performed using Anti-CHI3L1 Polyclonal Antibody (Product # PA5-81355) and a 42kDa band corresponding to Chitinase-3-like protein 1 was observed across in THP-1 compared to Jurkat which is reported to be negative. Whole cell extracts (30 µg lysate) of THP-1 (Lane 1), THP-1 treated with Protein Transport Inhibitor (1X for 4 hr) (Lane 2), Jurkat (Lane 3) and Jurkat treated with Protein Transport Inhibitor (1X for 4 hr) (Lane 4) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved prote... View More
产品信息
PA5-81355
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Mouse CHI3L1/YKL40 Protein (Met1-Ala381)
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Wet ice
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse CHI3L1/YKL40.
靶标信息
Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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