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OriGene
CHMP5 Monoclonal Antibody (OTI2E6), TrueMAB™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
CF808543
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2E6
抗原
Full length human recombinant protein of human CHMP5 produced in E.coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein family. These proteins are components of ESCRT-III, a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptosis-related protein PNAS-2; chromatin modifying protein 5; chromatin-modifying protein 5; HGNC:26942; hVps60; likely ortholog of H. sapiens SNF7 domain containing 2; small protein with inherent killing effect; SNF7 domain containing 2; SNF7 domain-containing protein 2; unnamed protein product; vacuolar protein sorting-associated protein 60
基因别名: 2210412K09Rik; C9orf83; CGI-34; HSPC177; PNAS-2; RGD1305968; SNF7DC2; Spike; Vps60
UniProt ID: (Human) Q9NZZ3, (Rat) Q4QQV8, (Mouse) Q9D7S9
Entrez Gene ID: (Human) 51510, (Rat) 297995, (Mouse) 76959
plasma membrane repair
regulation of receptor recycling
membrane budding
autophagy
nucleus organization
vacuolar transport
lysosome organization
mitotic metaphase plate congression
endosome to lysosome transport
regulation of centrosome duplication
erythrocyte differentiation
nuclear envelope reassembly
late endosome to vacuole transport via multivesicular body sorting pathway
viral budding via host ESCRT complex
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
viral budding
viral budding from plasma membrane
midbody abscission
cellular response to lipopolysaccharide
cellular response to muramyl dipeptide
multivesicular body sorting pathway
autophagosome maturation
regulation of mitotic spindle assembly
late endosome to lysosome transport
multivesicular body assembly
vesicle fusion with vacuole
multivesicular body-lysosome fusion
membrane fission
ESCRT III complex disassembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
