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PA5-34611 targets Chp1 in ChIP and WB applications and shows reactivity with Yeast samples.
The PA5-34611 immunogen is synthetic peptide conjugated to KLH derived from within residues 900 to the C-terminus of Schizosaccharomyces pombe Chp1.
PA5-34611 detects Chp1 which has a predicted molecular weight of approximately 109 kDa.
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Chromo domain-containing protein 1
基因别名: chp1; SPAC18G6.02c
UniProt ID: (Fission yeast) Q10103
Entrez Gene ID: (Fission yeast) 2542239