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Proteintech
CHRM3 Polyclonal Antibody
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产品信息
21978-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHRM3 fusion protein Ag17791
偶联物
形式
Liquid
浓度
0.4 mg/mL
规格
60 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: RTKELAGLQA SGTEAETENF VHPTGSSRSC SSYELQQQSM KRSNRRKYGR CHFWFTTKSW KPSSEQMDQD HSSSDSWNNN DAAASLENSA SSDEEDIGSE TRAIYSIVLK LPGHSTILNS TKLPSSDNLQ VPEEELGMVD LERKADKLQA QKSVDDGGSF PKSFSKLPIQ LESAVDTAKT SDVNSSVGKS TATLPLSFKE ATLAKRFALK TRSQITK
靶标信息
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor, muscarinic 3; AChR M3; cholinergic receptor; cholinergic receptor, muscarinic 3, cardiac; cytotransmitter gated ion channel; G protein coupled receptor; m3 muscarinic receptor; Mm3 mAChR; muscarinic acetylcholine receptor 3; Muscarinic acetylcholine receptor M3
基因别名: Chrm-3; CHRM3; EGBRS; HM3; M3; m3AChR; M3R; PBS
UniProt ID: (Human) P20309, (Mouse) Q9ERZ3, (Rat) P08483
Entrez Gene ID: (Human) 1131, (Mouse) 12671, (Rat) 24260
smooth muscle contraction
regulation of smooth muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
G-protein coupled acetylcholine receptor signaling pathway
chemical synaptic transmission
synaptic transmission, cholinergic
nervous system development
calcium-mediated signaling
positive regulation of insulin secretion
protein modification process
positive regulation of smooth muscle contraction
saliva secretion
acetylcholine receptor signaling pathway
ligand-gated ion channel signaling pathway
regulation of vascular smooth muscle contraction
digestion
sensory perception of chemical stimulus
regulation of vasoconstriction
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