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Proteintech
CHST8 Polyclonal Antibody
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产品信息
16426-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHST8 Fusion Protein Ag9669 (75-424 aa encoded by BC014250)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VTRDLSSGA PRGRNLPAPD QPQPPLQRGT RLRLRQRRRR LLIKKMPAAA TIPANSSDAP FIRPGPGTLD GRWVSLHRSQ QERKRVMQEA CAKYRASSSR RAVTPRHVSR IFVEDRHRVL YCEVPKAGCS NWKRVLMVLA GLASSTADIQ HNTVHYGSAL KRLDTFDRQG ILHRLSTYTK MLFVREPFER LVSAFRDKFE HPNSYYHPVF GKAILARYRA NASREALRTG SGVRFPEFVQ YLLDVHRPVG MDIHWDHVSR LCSPCLIDYD FVGKFESMED DANFFLSLIR APRNLTFPRF KDRHSQEART TARIAHQYFA QLSALQRQRT YDFYYMDYLM FNYSKPFADL Y (75-424 aa encoded by BC014250)
靶标信息
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the Golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; Carbohydrate sulfotransferase 8; GalNAc-4-O-sulfotransferase 1; GALNAC-4-ST1; GalNAc4ST-1; N-acetylgalactosamine-4-O-sulfotransferase 1
基因别名: 1500011J21Rik; AI426009; CHST8; GalNAc4ST; GALNAC4ST1; PSS3
UniProt ID: (Human) Q9H2A9, (Mouse) Q8BQ86
Entrez Gene ID: (Human) 64377, (Rat) 308511, (Mouse) 68947
N-acetylgalactosamine 4-O-sulfotransferase activity
N-acetylglucosamine 6-O-sulfotransferase activity
heparan sulfate 2-O-sulfotransferase activity
sulfotransferase activity
HNK-1 sulfotransferase activity
transferase activity
heparan sulfate 6-O-sulfotransferase activity
trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity
1-phenanthrol sulfotransferase activity
3-phenanthrol sulfotransferase activity
4-phenanthrol sulfotransferase activity
trans-3,4-dihydrodiolphenanthrene sulfotransferase activity
9-phenanthrol sulfotransferase activity
2-phenanthrol sulfotransferase activity
phenanthrol sulfotransferase activity
1-hydroxypyrene sulfotransferase activity
galactose 3-O-sulfotransferase activity
proteoglycan sulfotransferase activity
cholesterol sulfotransferase activity
hydroxyjasmonate sulfotransferase activity
transferase
metabolite interconversion enzyme
