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Invitrogen
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Product is supplied at 1 mL (100 µL/mL). Application notes: Flow Cytometry - This anitbody stains the extracellular domain of Mincle transfected 293 cells. It does not bind to other receptors in the rat APLEC family. Functional Assay - This antibody can act complementary in the inhibition of phagocytosis.
Positive control: BW5417 or 293T cells.
CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-type lectin domain family 4 member E; C-type lectin superfamily member 9; immunoreceptor; Macrophage-inducible C-type lectin; Mincle
基因别名: Clec4e; Clecsf9; Mincle
UniProt ID: (Rat) Q67EQ1
Entrez Gene ID: (Rat) 450223