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Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bifurcated 2; chronic lymphocytic leukemia deletion region gene 8 protein; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; isoform lacks exon 4; lysine N-methyltransferase 1F; PHD finger protein 11; SET domain; SET domain bifurcated 2; SET domain, bifurcated 2; similar to Setdb2 variant A but lacks 47 bps within exon 1; similar to Setdb2 variant A but utilizes an alternate splice acceptor site between exons 11 and 12, which results in a frame shift mutation and a premature stop codon; unnamed protein product; variant starts in exon 2
基因别名: C13orf4; CLLD8; CLLL8; Gm293; KMT1F
UniProt ID: (Human) Q96T68
Entrez Gene ID: (Human) 83852, (Rat) 100361710, (Mouse) 239122