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Invitrogen
CLSTN2 Polyclonal Antibody
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产品信息
PA5-47745
产品规格
种属反应
Human
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human Calsyntenin-2 Ser21-Thr834 (Val366Ile)
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Calsyntenin-1 and rhCalsyntenin-3 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
靶标信息
Calsyntenin 2 (CLSTN2) is a gene located on chromosome 3p22.2 that encodes a member of the calsyntenin family of proteins, which are characterized by their role in calcium binding and involvement in synaptic function and neural connectivity. CLSTN2 is predominantly expressed in the nervous system, where it contributes to synaptic organization and signaling processes essential for neural plasticity and cognitive functions. The protein is involved in mediating vesicular transport and axonal trafficking, influencing the establishment and maintenance of synaptic connections. Altered expression or mutations in CLSTN2 have been linked to neurological disorders, including Alzheimer's disease, suggesting its significance in maintaining neural circuit stability and memory processes. Current research continues to explore CLSTN2's functional roles in neurobiology, with potential therapeutic implications for enhancing synaptic function and addressing neurodegenerative conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alc-gamma; alcadein gamma; Alcadein-gamma; cadherin-related family member 13; Calsyntenin-2; CS2alcadein-gamma; FLJ39113; FLJ39499; MGC119560
基因别名: ALC-GAMMA; alcagamma; CDHR13; CLSTN2; CS2; CSTN2
UniProt ID: (Human) Q9H4D0
Entrez Gene ID: (Human) 64084
