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Invitrogen
COLQ Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-65418
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.3 mg/mL
规格
30 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PPGRCLCGPTM NVNNPSYGES VYGPSSPRVP VIFVVNNQEE LERLNTQNAI AFRRDQRSLY FKDSLGWLPI QLTPFYPVDY TA
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 84%.
靶标信息
COLQ (collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase), also known as EAD, is a 455 amino acid protein that localizes to the end plate of skeletal muscle. COLQ anchors the catalytic subunits of asymmetric AChE (acetylcholinesterase) to the basal lamina at the neuromuscular junctions of vertebrates. Mutations of COLQ lead to congenital myasthenic syndromes which are rare autosomal recessive diseases characterized by general weakness increased by exertion, ophthalmoplegia and refractoriness to anticholinesterase drugs. Eight isoforms exist due to alternative splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholinesterase-associated collagen; AChE Q subunit; AChE Q subunit; single strand of homotrimeric collagen-like tail subunit; collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; collagenic tail of endplate acetylcholinesterase; ColQ; single strand of homotrimeric collagen-like tail subunit of asymmetric acetylcholinesterase; unnamed protein product
基因别名: CMS5; EAD
UniProt ID: (Human) Q9Y215
Entrez Gene ID: (Human) 8292
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