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Invitrogen
COMP Monoclonal Antibody (MA37C94 (HC484D1))
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COMP Antibody (MA1-20221) in IHC
International journal of molecular sciences 2021 -
Figure 1 Retention of human mutant-COMP in ER of MT-COMP articular chondrocytes at 4 weeks, with CHOP expression at 12 weeks. All mice were administered DOX from birth to collection at 2, 4, 8, 12, 16, and 20 weeks. Dotted line marks the edge of articular cartilage. Control and MT-COMP tibial articular cartilages were immunostained using human COMP-specific antibodies (red) and protein disulfide isomerase (... View More
产品信息
MA1-20221
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse
宿主/亚型
Rat
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
MA37C94 (HC484D1)
抗原
Human cartilage derived COMP
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
MA1-20221 detects COMP in human samples.
MA1-20221 has been successfully used in ELISA, immunoprecipitation, immunohistochemistry (frozen and paraffin) and Western blot applications. Predicted molecular weight 82.8 kDa.
The MA1-20221 immunogen is human cartilage derived COMP.
靶标信息
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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