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Invitrogen
COX1 Polyclonal Antibody
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COX1 Antibody (PA1-85118) in WB
PloS one 2014 -
Figure 6 The effects of PRP (A) and HGF (B) treatment on COX-1 and COX-2 protein expression in tendon cell culture. Total proteins extracted from tendon cells after treatments were separated on 12% SDS-PAGE and transferred onto nitrocellulose membrane to detect COX-1 and COX-2 proteins using goat anti-COX-1 and goat anti-COX-2 polyclonal antibodies, respectively, and peroxidase-conjugated rabbit anti-goat I... View More
产品信息
PA1-85118
应用
建议稀释比
已发表文章
产品规格
已发表种属
Rabbit
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Native protein.
偶联物
形式
Liquid
保存条件
4°C or -20°C if preferred
运输条件
Wet ice
RRID
产品详细信息
Predicted to react with all mammals based on sequence homology.
靶标信息
PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
