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Proteintech
COX15 Polyclonal Antibody
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产品信息
11441-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
COX15 Fusion Protein Ag2004 (1-410 aa encoded by BC002382)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MQRLLFPPL RALKGRQYLP LLAPRAAPRA QCDCIRRPLR PGQYSTISEV ALQSGRGTVS LPSKAAERVV GRWLLVCSGT VAGAVILGGV TRLTESGLSM VDWHLIKEMK PPTSQEEWEA EFQRYQQFPE FKILNHDMTL TEFKFIWYME YSHRMWGRLV GLVYILPAAY FWRKGWLSRG MKGRVLALCG LVCFQGLLGW YMVKSGLEEK SDSHDIPRVS QYRLAAHLGS ALVLYCASLW TSLSLLLPPH KLPETHQLLQ LRRFAHGTAG LVFLTALSGA FVAGLDAGLV YNSFPKMGES WIPEDLFTFS PILRNVFENP TMVQFDHRIL GITSVTAITV LYFLSRRIPL PRRTKMAAVT LLALAYTQVG LGISTLLMYV PTPLAATHQS GSLALLTGAL WLMNELRRVP K (1-410 aa encoded by BC002382)
靶标信息
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family. Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues containing high rates of oxidative phosphorylation including brain, heart and muscle. COX15 defects are the cause of a neurodegenerative disorder known as Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: COX15 cytochrome c oxidase assembly homolog; COX15 homolog, cytochrome c oxidase assembly protein; cytochrome c oxidase assembly homolog 15; Cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15; HAS; Heme A synthase COX15
基因别名: 2900026G05Rik; CEMCOX2; COX15
UniProt ID: (Human) Q7KZN9, (Mouse) Q8BJ03
Entrez Gene ID: (Human) 1355, (Mouse) 226139
