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MA3-813 detects cellular retinoic acid binding protein I (CRABPI) from human, mouse, monkey, feline, bovine, rabbit, rat, turtle and chicken tissues. This antibody does not react with chameleon, goldfish and frog. This antibody does not cross-react with cellular retinol binding protein (CRBP), performic acid oxidized CRBP, interphotoreceptor retinoid binding protein or retinol binding protein.
MA3-813 has been successfully used in Western blot, immunohistochemistry and ELISA procedures. By Western blot, this antibody detects a 16 kDa protein representing CRABPI from rat retinal supernatant. Immunohistochemical staining of CRABPI in rat retina with MA3-813 results in its localization to amacrine somata and laminae in the inner plexiform layer.
The MA3-813 antigen is oxidized CRABPI from bovine retina.
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cellular retinoic acid binding protein I; cellular retinoic acid binding protein I (CRABP-I) homologue; Cellular retinoic acid-binding protein 1; Cellular retinoic acid-binding protein I; CRABP-I; retinoic acid-binding protein
基因别名: AI326249; cCRABP-I; CRABP; Crabp-1; CRABP-I; CRABP1; CRABPI; Rbp-5; RBP5
UniProt ID: (Human) P29762, (Bovine) P62964, (Chicken) P40220, (Rat) P62966, (Mouse) P62965
Entrez Gene ID: (Human) 1381, (Bovine) 282201, (Rabbit) 100338607, (Chicken) 374211, (Rat) 25061, (Mouse) 12903