Abnova

CREBL2 Monoclonal Antibody (1C1)

Name: CREBL2 Monoclonal Antibody (1C1)
Brand: Abnova
SKU: H00001389-M04

查看其他3个CREBL2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

图: 1 / 1

CREBL2 Antibody (H00001389-M04) in WB

Western Blot analysis of CREBL2 expression in transfected 293T cell line by CREBL2 monoclonal antibody (M04), clone 1C1. Lane 1: CREBL2 transfected lysate (Predicted MW: 13.8 KDa). Lane 2: Non-transfected lysate. .

Product Image Gallery

Immunogen image

Immunogen Image CREBL2 Monoclonal Antibody (1C1)

产品信息

H00001389-M04

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

1C1

抗原

CREBL2 (NP_001301.1, 1 a.a. approximately 120 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

Immunogen sequence: MDDSKVVGGK VKKPGKRGRK PAKIDLKAKL ERSRQSAREC RARKKLRYQY LEELVSSRER AICALREELE MYKQWCMAMD QGKIPSEIKA LLTGEEQNKS QQNSSRHTKA GKTDANSNSW

靶标信息

cAMP response element-binding protein-like-2 was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurrence of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。