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Abnova
CREM Polyclonal Antibody, MaxPab™
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产品信息
H00001390-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CREM (NP_001872.3, 1 a.a. approximately 137 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTMETVESQH DGSITASLTE SKSAHVQTQT GQNSIPALAQ VAAIAETDES AESEGVIDSH KRREILSRRP SYRKILNELS SDVPGVPKIE EERSEEEGTP PSIATMAVPT SIYQTSTGQY SMYAAIRYDT VLALSLL
靶标信息
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cAMP response element modulator; cAMP-responsive element modulator; CREM 2alpha-b protein; CREM 2beta-a protein; ICER; Inducible cAMP early repressor; inducible cAMP early repressor ICER; MGC111110; MGC17881; MGC41893; OTTHUMP00000019443
基因别名: CREM; CREM-2; hCREM-2; ICER
UniProt ID: (Human) Q03060
Entrez Gene ID: (Human) 1390
glucose metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
fatty acid metabolic process
glycosphingolipid metabolic process
signal transduction
multicellular organism development
spermatogenesis
cell differentiation
circadian regulation of gene expression
regulation of circadian rhythm
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
response to cAMP
