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Invitrogen
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Immunogen sequence: VLTLDILDVV TTDPPPDVHV SRVGGLEDQL SVRWVSPPAL KDFLFQAKYQ IRYRVEDSVD WKVVDDVSNQ TSCRLAGLKP GTVY
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。