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Immunogen sequence: NWNGPHRLYL QMSTHGKVRF RDIASPKFSM PSPVRTVITA DFDNDQELEI FFNNIAYRSS SANRLFRVIR REHGDPLIEE LNPGDALEPE GRGTGGVVTD FDGDGMLDLI LSHGESMAQP LSVFRGNQGF NNNWLRVVPR TRFGAFARGA KVVLYTKKSG AHLRIIDGGS GYLCEMEPVA HFGLGKDEAS SVEVTWPDGK MVSRNVASGE MNSVLEILYP RDEDTLQDPA PLECGQGFSQ QENGHCMDTN ECIQFPFVCP RDKPVCVNTY GSYRCRTNKK CSRGYEPNED GTACVGTLGQ SPGPRPTTPT AAAATAAAAA AAGAATAAPV LVDGDLNLGS VVKESCEPSC; Positive Samples: Mouse brain; Cellular Location: extracellular matrix, extracellular space
CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 68 kDa chondrocyte-expressed protein; ASPIC; Cartilage acidic protein 1; CEP-68; FLJ10320; Protein CRTAC1-B
基因别名: 2810454P21Rik; Aspic1; AW047536; Cep68; Crtac1; Crtac1B; Lotus
UniProt ID: (Mouse) Q8R555
Entrez Gene ID: (Mouse) 72832