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Proteintech
CSNK2A1 Polyclonal Antibody
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产品信息
10992-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CSNK2A1 Fusion Protein Ag1452 (1-391 aa encoded by BC011668)
偶联物
形式
Liquid
浓度
0.62 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSGPVPSRA RVYTDVNTHR PREYWDYESH VVEWGNQDDY QLVRKLGRGK YSEVFEAINI TNNEKVVVKI LKPVKKKKIK REIKILENLR GGPNIITLAD IVKDPVSRTP ALVFEHVNNT DFKQLYQTLT DYDIRFYMYE ILKALDYCHS MGIMHRDVKP HNVMIDHEHR KLRLIDWGLA EFYHPGQEYN VRVASRYFKG PELLVDYQMY DYSLDMWSLG CMLASMIFRK EPFFHGHDNY DQLVRIAKVL GTEDLYDYID KYNIELDPRF NDILGRHSRK RWERFVHSEN QHLVSPEALD FLDKLLRYDH QSRLTAREAM EHPYFYTVVK DQARMGSSSM PGGSTPVSSA NMMSGISSVP TPSPLGPLAG SPVIAAANPL GMPVPAAAGA QQ (1-391 aa encoded by BC011668)
靶标信息
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; casein kinase II, alpha 1 polypeptide; casein kinase II, alpha 1 related sequence 4; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; protein kinase CK2
基因别名: CK2A1; CKII; Ckiia; CSNK2A1; Csnk2a1-rs4; CSNK2A3
UniProt ID: (Human) P68400, (Mouse) Q60737, (Rat) P19139
Entrez Gene ID: (Human) 1457, (Mouse) 12995, (Rat) 116549
protein phosphorylation
positive regulation of cell proliferation
positive regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of protein catabolic process
protein autophosphorylation
regulation of catalytic activity
mitotic spindle checkpoint
regulation of cell growth
transcription, DNA-templated
regulation of transcription, DNA-templated
Wnt signaling pathway
regulation of cell proliferation
rhythmic process
protein folding
apoptotic process
signal transduction
chaperone-mediated protein folding
regulation of signal transduction by p53 class mediator
