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Invitrogen
CTC1 Polyclonal Antibody
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产品信息
PA5-24695
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 767-795 amino acids from the central region of human CQ068
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CQ068 is subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication. CQ068 also appears to function in a telomere-associated complex with OBFC1 and TEN1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: alpha accessory factor 132; conserved telomere capping protein 1; Conserved telomere maintenance component 1; CST complex subunit CTC1; HBV DNAPTP1-transactivated protein B
基因别名: AAF-132; AAF132; C17orf68; CRMCC; CTC1; tmp494178
UniProt ID: (Human) Q2NKJ3
Entrez Gene ID: (Human) 80169
telomere maintenance
cellular response to DNA damage stimulus
regulation of G2/M transition of mitotic cell cycle
telomere maintenance via telomere lengthening
multicellular organism growth
positive regulation of DNA replication
positive regulation of fibroblast proliferation
spleen development
thymus development
bone marrow development
negative regulation of telomerase activity
hematopoietic stem cell proliferation
replicative senescence
regulation of telomere maintenance via telomere lengthening
