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Proteintech
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Immunogen sequence: MLPLLLGLL GPAACWALGP TPGPGSSELR SAFSAARTTP LEGTSEMAVT FDKVYVNIGG DFDVATGQFR CRVPGAYFFS FTAGKAPHKS LSVMLVRNRD EVQALAFDEQ RRPGARRAAS QSAMLQLDYG DTVWLRLHGA PQYALGAPGA TFSGYLVYAD ADADAPARGP PAPPEPRSAF SAARTRSLVG SDAGPGPRHQ PLAFDTEFVN IGGDFDAAAG VFRCRLPGAY FFSFTLGKLP RKTLSVKLMK NRDEVQAMIY DDGASRRREM QSQSVMLALR RGDAVWLLSH DHDGYGAYSN HGKYITFSGF LVYPDLAPAA PPGLGASELL (1-329 aa encoded by BC035628)
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C1q/TNF-related protein 4; Complement C1q tumor necrosis factor-related protein 4; complement-c1q tumor necrosis factor-related protein 4
基因别名: 0710001E10Rik; 9430004J15Rik; C1QTNF4; CTRP4; ZACRP4
UniProt ID: (Human) Q9BXJ3, (Mouse) Q8R066
Entrez Gene ID: (Human) 114900, (Mouse) 67445, (Rat) 311184