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Invitrogen
CYP2C19 Polyclonal Antibody
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产品信息
PA1-84220
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Purified human CYP2C19 expressed in E.Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
This antibody is a specific and potent inhibitor of CYP2C19 activity.
靶标信息
CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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