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Invitrogen
CYP2C9 Polyclonal Antibody
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CYP2C9 Antibody (720237) in WB
Western blot analysis was performed on whole cell extracts (30 µg lysate) of Hep G2 (Lane 1), Tissue extracts of (30 µg lysate) Mouse liver (Lane 2), Rat liver (Lane 3), K-562 (Lane 4), HeLa (Lane 5), Jurkat (Lane 6) and Tissue extracts of (30 µg lysate) Mouse small intestine (Lane 7). The blots were probed with Anti-CYP2C9 Polyclonal Antibody (Product # 720237, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution).... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
720237
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptides corresponding to Human CYP2C9 (aa 185-203, 451-468, 84-97)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2-7.4, with 0.1% BSA, 30% glycerol
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Pig and Horse.
靶标信息
CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytochrome P-450 S-mephenytoin 4-hydroxylase; cytochrome P-450MP; cytochrome P450 PB-1; cytochrome P450, family 2, subfamily C, polypeptide 9; flavoprotein-linked monooxygenase; MGC149605; MGC88320; microsomal monooxygenase; unnamed protein product; xenobiotic monooxygenase
基因别名: CPC9; CYP2C; CYP2C10; CYPIIC9; P450-2C9; P450IIC9
UniProt ID: (Human) P11712
Entrez Gene ID: (Human) 1559
monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
steroid hydroxylase activity
arachidonic acid 14,15-epoxygenase activity
arachidonic acid 11,12-epoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
(S)-limonene 6-monooxygenase activity
(S)-limonene 7-monooxygenase activity
heme binding
caffeine oxidase activity
(R)-limonene 6-monooxygenase activity
estrogen 2-hydroxylase activity
arachidonate 8,9-epoxygenase activity
fatty acid omega-1 hydroxylase activity
terpenoid metabolic process
xenobiotic metabolic process
steroid metabolic process
cholesterol metabolic process
estrogen metabolic process
monoterpenoid metabolic process
arachidonic acid metabolic process
epoxygenase P450 pathway
urea metabolic process
monocarboxylic acid metabolic process
xenobiotic catabolic process
long-chain fatty acid biosynthetic process
icosanoid biosynthetic process
oxidative demethylation
cellular organofluorine metabolic process
omega-hydroxylase P450 pathway
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
