Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
Cadherin-17 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
24339-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Cadherin-17 Fusion Protein Ag19488 (89-406 aa encoded by BC113464)
偶联物
形式
Liquid
浓度
0.41 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RSTHNLQVA ALDANGIIVE GPVPITIEVK DINDNRPTFL QSKYEGSVRQ NSRPGKPFLY VNATDLDDPA TPNGQLYYQI VIQLPMINNV MYFQINNKTG AISLTREGSQ ELNPAKNPSY NLVISVKDMG GQSENSFSDT TSVDIIVTEN IWKAPKPVEM VENSTDPHPI KITQVRWNDP GAQYSLVDKE KLPRFPFSID QEGDIYVTQP LDREEKDAYV FYAVAKDEYG KPLSYPLEIH VKVKDINDNP PTCPSPVTVF EVQENERLGN SIGTLTAHDR DEENTANSFL NYRIVEQTPK LPMDGLFLIQ TYAGMLQLA (89-406 aa encoded by BC113464)
靶标信息
CDH17 gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BILL-cadherin; Cadherin; cadherin 17, LI cadherin (liver-intestine); cadherin-16; Cadherin-17; FLJ26931; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; Intestinal peptide-associated transporter HPT-1; LI cadherin; LI-cadherin; Liver-intestine cadherin; MGC138218; MGC142024; P130
基因别名: CDH16; CDH17; HPT-1; HPT-1/LI; HPT1
UniProt ID: (Human) Q12864, (Mouse) Q9R100
Entrez Gene ID: (Human) 1015, (Mouse) 12557
germinal center B cell differentiation
marginal zone B cell differentiation
transport
oligopeptide transport
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
integrin-mediated signaling pathway
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
positive regulation of integrin activation by cell surface receptor linked signal transduction
adherens junction organization
oligopeptide transmembrane transport
spleen development
