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Invitrogen
Calcitonin Monoclonal Antibody (4-5)
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产品信息
MA3-021A
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
4-5
抗原
Salmon calcitonin.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
MA3-021A detects calcitonin (CT) from salmon tissues. This antibody cross reacts with glycine-extended salmon calcitonin, but is unreactive with salmon calcitonin peptides 23-30 and 26-32. It shows no cross reactivity with human calcitonin.
MA3-021A has been successfully used in ELISA procedures. By ELISA this antibody is useful in solid-phase or competitive solution based procedures with a sensitivity of approximately 50 ng/mL.
The MA3-021A antigen is salmon calcitonin. This antibody was raised against salmon calcitonin which, as in the naturally occurring peptide, contains a C-terminal prolinamide. The epitope recognized likely lies in the N-terminal portion of the molecule.
Reconstitute with PBS.
靶标信息
Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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