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MA5-15272 targets Calcyclin in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.
The MA5-15272 immunogen is purified recombinant fragment of calcyclin expressed in E. Coli.
Calcyclin is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2A9; 5B10; CABP; CACY; CacyBP; Calcyclin; Calcyclin-binding protein; growth-inhibiting gene 5 protein; hCacyBP; PRA; RP1-102G20.6; S100A6; S100A6-binding protein; Siah-interacting protein; Siah-interacting protein (SIP)
基因别名: CACYBP; GIG5; PNAS-107; S100A6BP; SIP
UniProt ID: (Human) Q9HB71
Entrez Gene ID: (Human) 27101