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Proteintech
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Immunogen sequence: YWHTTFYEG SWRRGSSAGG CRNHPGTFWT NPQFKISLPE GDDPEDDAEG NVVACTCLVA LMQKNWRHAR QQGAQLQTIG FVLYAVPKEF QNIQDVHLKK EFFTKYQDHG FSEIFTNSRE VSSQLRLPPG EYIIIPSTFE PHRDADFLLR VFTEKHSESW ELDEVNYAEQ LQEEKVSEDD MDQDFLHLFK IVAGEGKEIG VYELQRLLNR MAIKFKSFKT KGFGLDACRC MINLMDKDGS GKLGLLEFKI LWKKLKKWMD IFRECDQDHS GTLNSYEMRL VIEKAGIKLN NKVMQVLVAR YADDDLIIDF DSFISCFLRL KTMFTFFLTM DPKNTGHICL SLEQWLQMTM WG (352-702 aa encoded by BC033733)
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium-activated neutral proteinase 11; calcium-activated neutral proteinase 11 {ECO:0000250|UniProtKB:Q9UMQ6}; calcium-dependent thiol protease; Calpain 11; calpain 11 {ECO:0000312|EMBL:AAH97256.1}; Calpain-11; CANP 11; CANP 11 {ECO:0000250|UniProtKB:Q9UMQ6}; capn11; capn11 {ECO:0000312|RGD:1302946}; HIP2; LIG
基因别名: calpain11; CAPN11
UniProt ID: (Human) Q9UMQ6, (Rat) Q4V8Q1, (Mouse) Q6J756
Entrez Gene ID: (Human) 11131, (Rat) 408218, (Mouse) 268958